NOCANTHER Nanomedicine upscaling for early clinical phases of multimodal cancer therapy

Prof. Rodolfo Miranda (PI), Dr. Alvaro Somoza (PI)

Funding :

H2020-NMP-2015-two-stage no 685795

Duration: 2016 - 2021

60 months

The NoCanTher consortium aims to scale-up a magnetic nanoparticle formulation based on iron oxide and assess it in a clinical study for the treatment of pancreatic cancer with an alternating magnetic field generator. The combination of the particles and the magnetic field at the tumoral area will increase the temperature inducing the death of tumoral cells. This process is known as magnetic hyperthermia where, remarkably, cancer cells are more sensitive than healthy cells, reducing, therefore, the undesired side effects present in conventional approaches.